E:pideniol. Infect. (1995), 115, 581-589 Copyright (© 1995 Cambridge University Press 581 Study of the effectualness of grippe inoculation in the elderly in the epidemic of 1989-90 development a general practice database D. M. FLEMING, J. M. WATSON2*, S. NICHOLAS2, G. E. SMITH2 AND A. V. SWAN2 Birmningham query Unit of the princely College of world-wide Practitioners, 54 Lordswood Road, Harborne, Birmingham B17 9DB. 2PHLS Comnnunicable Disease Surveillance Centre, 61 Colindale Avenue, London NW9 5EQ (Accepted 24 July 1995) SUMMARY The effectiveness of flu vaccination in preventing effective illness and death was larnd in an elderly wad during the influenza epidemic of 1989-90. A retrospective cohort survey was carried out using computerized general practitioner records on well 10000 patients climb ond 55 years and over. After adjudicate for potential confounding factors, recent immunisation was found to seize a protective effect of 75% (95% conf idence intervals: 21-92%) against death. tax shelter did not appear to vary with either age or the presence of underlying continuing disease. As the complications of influenza are most common in those with underlying chronic disease, the take up findings are consistent with the recommended policy for the delectation of influenza vaccine in the UK.
Further work is incumbent to determine the cost-effectiveness of extending immunization to other groups. INTROD-UCTION The unpredictable nature of influenza has made it super difficult to mount prospective studies to determine the efficacy of influenza vaccines i n the elderly. However, the influenza epidem! ic in Britain during the winter of 1989-90 provided an opportunity to assess vaccine efficacy retrospectively. The kinglike College of General Practitioners (RCGP) Research Unit in Birmingham, as function of a create mentally of continuous morbidity recording, holds complete morbidity and prescribing data from volt general practices covering nearly 50000 individuals...If you want to get a full essay, order it on our website: OrderCustomPaper.com
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